| Similar Articles |
 |
Chemistry World March 19, 2009 Manisha Lalloo |
Copper catalysts give meta aromatics UK Researchers have discovered that, simply by using a copper catalyst, they are able to perform tricky substitution reactions at a difficult position on benzene rings  |
Chemistry World May 24, 2007 James Mitchell Crow |
Palladium Coupling in Fewer Steps Look out Suzuki - Canadian chemists have successfully joined up simple benzene ring-like aromatics without any pre-activation.  |
Chemistry World July 9, 2012 Phillip Broadwith |
'Molecular cobra' turns C-H to C=C A reagent developed by US chemists can selectively introduce synthetically useful C=C double bonds into unactivated carbon chains, guided by an activating group attached to a nearby oxygen or nitrogen atom.  |
Chemistry World November 27, 2009 Simon Hadlington |
A simple way to join an olefin to an arene Chemists in the US have developed a simple and effective way to carry out a key class of reaction in organic synthesis - the bolting an olefin to an aromatic ring.  |
Chemistry World April 14, 2009 Lewis Brindley |
Osmium and pyridine ring together Organic chemists in China have found a way to put osmium into a pyridine ring - leading to the synthesis of the first metallapyridinium complex.  |
Chemistry World August 17, 2009 James Urquhart |
New method for fluorinating compounds Fluorine atoms are incorporated into aromatic organic compounds for many reasons, including their ability to increase metabolic stability, solubility and bioavailability.  |
Chemistry World May 22, 2015 James Urquhart |
Complex amines made easy (and cheap) Phil Baran's lab at the Scripps Research Institute, La Jolla, has come up with a protocol that repurposes two readily available and inexpensive feedstock building blocks; olefins and nitroarenes, via iron-catalysed cross-coupling.  |
Chemistry World August 14, 2014 Elisabeth Ratcliffe |
Photoredox route to medically-important heterocycles Researchers in the US have developed a new photo catalyzed coupling reaction that could provide a pathway to a huge number of biologically active compounds.  |
Chemistry World April 28, 2011 Simon Hadlington |
New method for aromatic coupling Chemists in Switzerland have developed a way to couple aromatic rings through the Friedel-Crafts mechanism - something many people would have believed impossible.  |
Chemistry World August 2008 |
Column: In the pipeline Problems develop when there are too few workhorse reactions, which may well generate compounds that are too similar to each other. Are we at that stage now?  |
Chemistry World November 1, 2007 Richard Van Noorden |
Step Change for Organic Synthesis US chemists discovered how to attack a complex molecule's unreactive carbon-hydrogen bonds, without resorting to wasteful synthetic aids like protecting and directing groups.  |
Chemistry World November 2010 |
Carbon Couplers Take the Prize Three giants of organic chemistry, who pioneered palladium-catalysed cross coupling reactions, have shared this year's Nobel prize.  |
Chemistry World March 24, 2015 Karl Collins |
Back to basics for silylation While silicon is probably most familiar in organic synthesis as part of protecting groups, its utility extends much further.  |
Chemistry World March 14, 2014 Simon Hadlington |
Chemists make headway on C--H activation challenges Jin-Quan Yu's group at the Scripps Research Institute at La Jolla, California, have synthesized a library of synthetic chiral amino acids which could have applications in the pharmaceutical industry.  |
Chemistry World October 22, 2008 Susan Aldridge |
A greener route to amines Researchers based in Israel have developed an easier way to make troublesome primary amines, using a new ruthenium catalyst.  |
Chemistry World October 12, 2015 Emma Stoye |
Chemistry Nobel laureate Richard Heck dies Richard Heck, the organic chemist who shared the 2010 chemistry Nobel prize with for developing palladium-catalyzed cross coupling reactions, has died aged 84.  |
Chemistry World July 20, 2006 Jessica Ebert |
Golden Touch for Amines Aminobenzene chemicals are used to make anything from dyes to pharmaceuticals, and now scientists have found a way to produce them in a more efficient way using a gold catalyst.  |
Chemistry World August 11, 2010 Simon Hadlington |
Non-metal-catalysed C-C coupling Chinese chemists have successfully coupled aromatic molecules without the use of a transition metal catalyst - something that people have been trying to do for years with little success.  |
Chemistry World June 24, 2010 Phillip Broadwith |
Aryl rings get a fluorine fix A mild and effective method for coupling trifluoromethyl groups on to aryl rings has been developed by US chemists.  |
Chemistry World December 19, 2010 Simon Hadlington |
Novel route to key aromatics US chemists have found a new way to create aromatic compounds from straight chains of hydrocarbons by using an iridium-based catalyst.  |
Chemistry World March 25, 2011 Simon Hadlington |
New synthesis for chiral anticancer compound The promising anticancer compound nutlin-3 is likely to become more widely available to researchers thanks to a new synthetic protocol developed by US chemists.  |
Chemistry World June 10, 2010 Phillip Broadwith |
A green and salty chiral catalyst An efficient, chiral, salt-based hypervalent iodine catalyst has been discovered by Japanese chemists that could replace toxic metal catalysts without generating the waste or explosion risks associated with hypervalent organo-iodine complexes.  |
Chemistry World November 2, 2015 |
Batzelladine B Of all the diverse substances that nature produces, the alkaloids -- small molecules containing basic nitrogen -- have had the greatest impact on human history and health.  |
Chemistry World July 1, 2012 Paul Docherty |
Vincorine Cage-structured natural products are some of the most appealing (if perhaps not appetising) targets for organic chemists -- perhaps due to their obvious intricacy of form, but also because of their structural rigidity.  |
Chemistry World June 2011 |
Column: Totally Synthetic I've never heard of the Polonovski-Potier reaction, the keystone of a remarkable synthesis by a team led by Tohru Fukuyama at the University of Tokyo, Japan.  |
Chemistry World April 21, 2011 James Urquhart |
Lignin cut down to size by nickel catalyst A nickel-based homogeneous catalyst that breaks down lignin - the tough polymer that forms plant cell walls - into useful building blocks suitable for chemicals, including green fuels, has been developed by US scientists.  |
Chemistry World July 3, 2015 Andy Extance |
Copper catalysis overcomes double bond trouble Some carbon-carbon double bonds seem too unreactive for synthetic use -- but that's just how chemists in the US are now exploiting them.  |
Chemistry World January 27, 2010 Phillip Broadwith |
Cracking carbon-carbon bonds Chemists in the US have discovered a tungsten complex that can break a strong carbon-carbon bond in an aromatic ring.  |
Chemistry World April 15, 2010 Simon Hadlington |
Lead joins the aromatic ring club Scientists in Japan have successfully incorporated an atom of lead into an aromatic molecule - the heaviest metal so far to be 'aromatised'.  |
Chemistry World January 29, 2010 Phillip Broadwith |
Silicon goes aromatic Chemists in the UK have constructed a structural analogue of benzene made from silicon atoms. The molecule is not flat like benzene, but it reveals a new type of aromatic stabilisation.  |
Chemistry World February 2010 Paul Docherty |
Column: Totally Synthetic Palau'amine is an alkaloid which has stubbornly held off synthesis for over 15 years. Its nemesis comes in the form of Phil Baran at the Scripps Research Institute, La Jolla, US.  |
Chemistry World May 28, 2015 Matthew Gunther |
Purely inorganic aromatic ion synthesized Scientists in the US have successfully synthesized an aromatic ion made from only nitrogen and phosphorus. The anion is a rare example of a stable aromatic species containing no carbon atoms.  |
Chemistry World December 9, 2013 Jessica Cocker |
Hydrogen breaks strong bonds with brute force A method developed by Leo Lau of Western University in Canada and colleagues can break C -- H bonds without damaging the rest of the molecule.  |
Chemistry World January 28, 2015 |
Rubriflordilactone A It's likely that organic chemists have been practicing retrosynthesis in one form or another for at least a century, and certainly for decades before E J Corey formalized the concept in the mid-1990s  |
Chemistry World July 30, 2013 Paul Docherty |
Melotenine A Chirality, where would we be without you? Often the bane of the synthetic chemist's life, the challenge of asymmetry is perhaps what makes total synthesis so endlessly intriguing.  |
Chemistry World April 28, 2014 Simon Hadlington |
Elusive sigma aromaticity captured Chemists in the US have created a unique transition metal hydride in which the hydrogens form a five-membered aromatic ring, something that had been theorized, but until now never seen.  |
Chemistry World May 30, 2013 Andy Extance |
Catalyst duo exerts powerful stereocontrol Chemists from the Swiss Federal Institute of Technology, ETH Zurich, have teamed chiral catalysts in pairs to selectively drive a reaction towards desired stereoisomeric products with high selectivity.  |
Chemistry World April 18, 2012 Elinor Richards |
Homogeneous Catalyst Recovery Made Easier Scientists have now found a way to recover homogeneous catalysts at the end of a chemical reaction that doesn't suffer from the slow reaction rates that affect current catalyst recovery systems.  |
Chemistry World June 28, 2013 Anthony King |
Titanium takes on Haber -- Bosch process The synthesis of ammonia under milder condition, using less energy and fewer resources, has moved a step closer.  |
Chemistry World July 16, 2009 Simon Hadlington |
Strange vibrations Researchers in Taiwan have shown that in a relatively simple molecular system the induced vibrations can inhibit the breaking of the bond and slow the reaction down.  |
Chemistry World December 16, 2011 Kate McAlpine |
Radical experiment assesses interstellar nitrogen Radical reactions are challenging to measure at cold temperatures, but an international team of researchers have recently clocked the rate for atomic nitrogen and hydroxyl radicals at 56K.  |
Chemistry World June 2008 Sarah Houlton |
Breaking the rules The author finds out about some chemical tricks that can give a new drug the best possible odds of success  |
Chemistry World August 11, 2011 Josh Howgego |
Enzyme Inspired Nickel Complex Races to Produce Hydrogen A cheap nickel catalyst could pave the way for the industrial production of hydrogen - a step on the road to a hydrogen economy.  |
Chemistry World February 28, 2013 Paul Docherty |
Lyconadin A Since its isolation from the clubmoss Lycopodium complanatum in 2001, lyconadina A has been party to three total syntheses. All that interest stems from anti-Alzheimer's activity attributed to the lycopodium family.  |
Chemistry World March 6, 2015 James Morey |
Catalytic arylation methods: from the academic lab to industrial processes What if you wanted to arylate a sulfur atom instead of a carbon? Or build up the aryl group from scratch? I suggest turning to Catalytic arylation methods as your first port of call.  |
Chemistry World March 2012 Paul Docherty |
Column: Totally Synthetic Ring strain is a fascinating phenomenon - one that is best understood with plastic modelling kits, wearing safety specs for ring sizes of four or less.  |
Chemistry World November 2011 Paul Docherty |
Column: Totally Synthetic Gelsemoxonine has an extra four-membered azetidine ring, making for a considerable synthetic challenge.  |
Chemistry World July 23, 2012 Andrea Sella |
Chattaway's spatula Frederick Chattaway British chemist (1860-1944), was a careful and painstaking explorer of the chemical world. He studied some of the most dangerous compounds known, and was prepared to drop academic security for something more interesting.  |