| Similar Articles |
 |
Chemistry World July 2, 2014 Tim Wogan |
Miller's forgotten experiments point to primitive protein genesis Stanley Miller's experiments are still adding to our understanding of prebiotic Earth.  |
Chemistry World October 12, 2015 Andy Extance |
'Chemical search engine' backs alternative route to life A key class of biological molecules neglected in the search for life's chemical origins could have appeared spontaneously before organisms, UK scientists say.  |
Chemistry World November 1, 2009 Hayley Birch |
How light gave life a helping hand A new theory for how 'handedness' in organic molecules evolved has been proposed by Dutch scientists.  |
Chemistry World January 17, 2014 Katia Moskvitch |
Life may have begun in a tiny water droplet Chemical reactions run much faster and more efficiently when they take place in tiny droplets rather than in freestanding water -- such as a puddle or a lake, say researchers.  |
Chemistry World January 21, 2011 Russell Johnson |
Jump starting prebiotic photochemistry Light activated reactions of organic molecules in fatty acid membranes offers a plausible method for energy transfer and storage in prebiotic systems, claim US scientists.  |
Chemistry World December 5, 2012 Phillip Broadwith |
Chemical reactions in hot water Chinese and Japanese chemists have highlighted hot water's ability to promote unexpected reactions without any other reagents or catalysts. The work should expand our understanding of how to harness the physicochemical properties of water to potentially replace more complex reagents and catalysts.  |
Chemistry World November 25, 2014 James Urquhart |
Nanomolar chemistry enables 1500 experiments in a single day Chemists have conducted over 1500 chemistry experiments in under a day thanks to a miniaturized, high throughput automation platform they developed for identifying how synthetic molecules react under various conditions.  |
Chemistry World August 10, 2015 Kira Welter |
Peptide glue may have held first protocell components together Electrostatic interactions induced by short, positively charged, hydrophobic peptides are all it takes to attach RNA to vesicle membranes.  |
Chemistry World March 8, 2010 Lewis Brindley |
Molecular midwives helped birth of DNA 'Molecular midwives' - are compounds that played a crucial role in combining small nucleotide fragments into the first genetic polymeric material.  |
Chemistry World April 8, 2008 Mark Peplow |
Meteorite Source for Life's Handedness Scientists have long speculated that life's preference for left-handed amino acids may have been triggered by compounds brought to Earth by meteorites. Now they've shown exactly how two crucial steps in this process could happen.  |
Chemistry World January 19, 2010 Simon Hadlington |
New 'click' reaction to modify proteins Chemists in the US have discovered a new way to attach small molecules to proteins and peptides under mild, aqueous reaction conditions.  |
Chemistry World October 14, 2009 James Urquhart |
New route to amino acids US scientists have found a new way of making a class of non-natural amino acids that are widely used as components of pharmaceuticals and chiral catalysts.  |
Chemistry World October 16, 2008 Hayley Birch |
Miller's legacy: new clues to origins of life Scientists have re-examined dried residues in 50-year-old vials from classic 'primordial soup' experiments to glean new information about how life originated on Earth.  |
Chemistry World October 26, 2006 Victoria Gill |
Volcanoes Reveal the Secret of the Origin of Life Life began with a chemical reaction under the sea over four billion years ago. That is the claim of a German scientist whose team has recreated a crucial part of the reaction, synthesizing all the necessary ingredients for a living organism.  |
Chemistry World October 15, 2012 Melissae Fellet |
Synthesis by mass spectrometry Chemists have used mass spectrometry, commonly used to analyze molecules, to synthesize them on the microscale.  |
Chemistry World August 2, 2011 Phillip Broadwith |
Protein synthesis hijacked to turn out cyclic peptides Japanese researchers have developed a way of reprogramming the genetic code and using bacteria to make and screen huge libraries of cyclic peptides using unnatural amino acids.  |
Chemistry World August 2008 |
Column: In the pipeline Problems develop when there are too few workhorse reactions, which may well generate compounds that are too similar to each other. Are we at that stage now?  |
Chemistry World March 29, 2012 Simon Hadlington |
Seeds of life incubated in proto-planetary nurseries New findings imply that the organic chemistry required to produce the necessary molecules for life is part of the normal processes of planet formation.  |
Chemistry World June 16, 2011 |
Forming the First Sugars with Formose Reactions Hydrothermal synthesis could provide greener synthesis methods as well as information about the origin of life.  |
Chemistry World May 20, 2015 Katrina Kramer |
Taking the lead on drug discovery Researchers from the UK have developed a straightforward strategy for making compounds that have the potential to become clinical drugs.  |
Reactive Reports Issue 67 David Bradley |
Multichannel Microchemical Factory The microchemical factory approach offers a safer and scaleable approach to producing materials from the very smallest quantities to the largest bulk.  |
Chemistry World September 24, 2009 Phillip Broadwith |
Carbon can't but tin can US chemists have discovered that distannynes - tin-based analogues of acetylenes - can react reversibly with ethene to make cyclic complexes.  |
Chemistry World May 29, 2015 Derek Lowe |
Magic molecule modifiers The synthesis of a new organic molecule can be approached in several ways.  |
Chemistry World September 9, 2011 James Mitchell Crow |
High-throughput catalyst screening for the masses Using nothing more than the standard chemistry lab equipment, researchers in the US have successfully turned the discovery of new catalytic reactions into a high-throughput process.  |
Chemistry World March 2, 2007 Philip Ball |
Giving Life a Hand Why are proteins left-handed and nucleic acids right-handed? Once offered only a few sketchy theories, scientists have found more alternatives for creating homochirality.  |
Chemistry World March 22, 2007 Michael Gross |
Eat Isotopes to Live Longer Food containing heavy isotopes of hydrogen, carbon and nitrogen could slow down the aging process. That's the claim of a biochemist who suggests that seeding key biological molecules with deuterium or carbon-13 could drastically reduce oxidative damage or even avert it altogether.  |
Chemistry World February 27, 2009 Hayley Birch |
More data from mixtures via NMR Finnish scientists have developed a new technique for separating out the NMR spectra of compounds in a mixture.  |
Chemistry World September 16, 2014 Patrick Walter |
Computer simulations point to formamide as prebiotic intermediate in 'Miller' mixtures Formamide may have played a key role in the genesis of life  |
Chemistry World January 3, 2012 Simon Hadlington |
One-pot synthesis creates anticancer candidates Researchers in Germany have developed a simple, rapid and high-yielding cascade synthesis of a collection of polycyclic compounds that resemble indole alkaloid natural products and which interfere with cell division.  |
Chemistry World February 15, 2011 Mary Badcock |
Building up a natural product toolkit US scientists have come up with a method that makes it easier to extract compounds that are difficult to isolate from crude natural product mixtures.  |
Technology Research News June 29, 2005 |
Self-assembly: the natural way to make things In biology, there are a few different ways DNA molecules can be replicated and combined.  |
Chemistry World September 12, 2010 Mike Brown |
Comet shockwaves helped stimulate life on Earth The shock waves caused as comets hit the early Earth could have helped promote the formation of amino acids and the early building blocks of life, say US researchers.  |
Chemistry World June 17, 2013 Eleanor Merritt |
Switching chirality in amino acids An international team of scientists has developed a purely chemical approach to interconvert L- and D-amino acids. This method could rival enzymatic routes used in industry, and enable cheaper production of some pharmaceuticals.  |
Chemistry World September 7, 2014 Michael Gross |
Bringing chemical synthesis to the masses The promise of a novel approach to building chemical libraries, which only requires simple building blocks in water, without any additional reagents or sample preparation, is inspired by nature.  |
Chemistry World June 23, 2015 Derek Lowe |
Missing the target There are enzymes that no mustard has ever cut, to steal a phrase from science fiction author James Blish. Phosphatases, the flip side of kinase activity, are a perfect example.  |
Chemistry World November 24, 2006 Richard Van Noorden |
Cooking up Nano-Fusilli Here's a new twist on nanotubes: chemists have found a set of organic molecules that spontaneously assemble themselves into a helical spiral with a hollow core.  |
Chemistry World December 8, 2008 Hayley Birch |
Meteorites hitting oceans may have kick-started life Japanese scientists have done laboratory experiments to test the idea.  |
Chemistry World March 12, 2015 Matthew Gunther |
Chemical building blocks produce a wellspring of organic molecules Scientists in the US have developed an automated platform to create small organic molecules from a set of simple of chemical building blocks.  |
Chemistry World September 29, 2015 |
Navigating chemical space How big is chemistry? I don't mean how important is it, or how many people do it, but rather, how many molecules are there that we could make?  |
Chemistry World October 13, 2011 Phillip Broadwith |
Following Electrons' Chemical Reaction Quickstep The oscillating electronic states of molecules nearby and passing through a conical intersection can now be probed directly.  |
Chemistry World June 11, 2009 James Urquhart |
Enzyme-free assembly of DNA-like molecules US scientists have developed a simple peptide nucleic acid system that self-assembles and adapts to new instructions without enzymes.  |
Chemistry World February 11, 2013 Philip Ball |
A (chemical) potential theory of life's origin This theory says that life arose at hydrothermal vents, not merely because these provide heat and the ingredients for making complex organics but because they create sustained gradients of ion concentration.  |
Chemistry World January 20, 2014 David Bradley |
Molecular librarians create druglike collections Finding biologically active small molecules with pharmaceutical potential is a bittersweet process. Now, a new approach to building libraries of diverse alkaloid-type structures has been developed by US chemists.  |
Chemistry World August 20, 2008 |
Spying on Self-Assembly Proteins attaching to gold nanoparticles don't mill around randomly, but organise into clusters, according to UK scientists who say they have for the first time spied in detail peptides assembling on a surface.  |
Chemistry World August 2009 Derek Lowe |
Column: In the pipeline The author considers what makes a good looking drug molecule - and how beauty is in the eye of the beholder  |
Chemistry World October 9, 2006 Michael Gross |
Miniature Microbicides Researchers have created miniature antimicrobial peptides that contain only four (as opposed to the usual 12-50) amino acid residues combined with a fatty acid.  |
Chemistry World August 22, 2014 Derek Lowe |
Death of a reagent Anyone who's been practicing organic chemistry for a while can think back to reactions and reagents that were once in far wider use than they are today.  |
Wired Erin Biba |
Molecular Frameworks, the Building Blocks of All Life The world is complicated, but not as complicated as you might think. Most organic molecules derive from a few relatively simple architectures.  |
Chemistry World December 10, 2014 |
Big pharma opens up abandoned drugs Sixty eight stalled pharmaceutical compounds are being made available for academic research through the UK Medical Research Council.  |
Chemistry World November 30, 2007 Lewis Brindley |
Crystal Clear Structure Prediction One team of researchers has hit the jackpot by correctly predicting the crystal structures of four organic molecules in a competition organized by the University of Cambridge.  |