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Chemistry World December 20, 2007 Richard Van Noorden	Off-the-Peg Organic Synthesis Goes Commercial Chemists have created an efficient way to make small molecules by repeatedly using just one coupling reaction to clip together pre-prepared chemical fragments is going commercial.
Chemistry World November 3, 2008 Simon Hadlington	Organic synthesis set for auto-pilot Peptides are routinely made by machines that couple together amino acid components. Could organic synthesis ever get this simple?
Chemistry World October 2010	Column: In the pipeline Derek Lowe investigates the comeback combinatorial chemistry has made in the field of drug discovery
Chemistry World August 2, 2011 Phillip Broadwith	Protein synthesis hijacked to turn out cyclic peptides Japanese researchers have developed a way of reprogramming the genetic code and using bacteria to make and screen huge libraries of cyclic peptides using unnatural amino acids.
Chemistry World January 19, 2010 Simon Hadlington	New 'click' reaction to modify proteins Chemists in the US have discovered a new way to attach small molecules to proteins and peptides under mild, aqueous reaction conditions.
Chemistry World October 12, 2015 Andy Extance	'Chemical search engine' backs alternative route to life A key class of biological molecules neglected in the search for life's chemical origins could have appeared spontaneously before organisms, UK scientists say.
Chemistry World May 6, 2008 James Mitchell Crow	Building Peptides From the Wrong End UK chemists have cracked a long-standing problem in peptide synthesis that has prevented amino acid chains being grown from both ends. The insight could open up efficient ways to make peptide-based drugs.
Chemistry World February 7, 2007 Bea Perks	Protein's Non-Natural Alternative Beta peptides are of interest because of what they can tell researchers about protein folding in general. Now, chemical biologists have built what they say is a 'remarkably protein like' structure from beta peptides.
Bio-IT World August 18, 2004 Kevin Davies	In Praise of Chemical Diversity How to build better small-molecule libraries.
Reactive Reports Issue 58	ID Tags for Teenage Molecules One academic team has developed a logical technology that allows them to generate millions of unique tags to track sub-microscopic objects.
Chemistry World May 29, 2015 Derek Lowe	Magic molecule modifiers The synthesis of a new organic molecule can be approached in several ways.
Chemistry World May 20, 2015 Katrina Kramer	Taking the lead on drug discovery Researchers from the UK have developed a straightforward strategy for making compounds that have the potential to become clinical drugs.
HHMI Bulletin Nov 2011 Sarah C. P. Williams	Living Chemistry Biologists understand better what chemists can bring to the table. And chemists understand better the questions that biologists really care about. This has led to a bigger impact of chemists on biological problems.
Chemistry World May 31, 2009 Nina Notman	The natural approach to winning at drug discovery High throughput drug screening is often described as a casino, with the odds stacked on the side of success as long as a big enough library is used.
Chemistry World March 12, 2015 Matthew Gunther	Chemical building blocks produce a wellspring of organic molecules Scientists in the US have developed an automated platform to create small organic molecules from a set of simple of chemical building blocks.
Bio-IT World February 10, 2003 Malorye Branca	Conquering Infinity with Chemical Genetics Harvard superchemist Stuart Schreiber defines the convergence of chemistry and biology. Now the field of chemical genetics is heading toward the clinic.
Chemistry World August 2008	Column: In the pipeline Problems develop when there are too few workhorse reactions, which may well generate compounds that are too similar to each other. Are we at that stage now?
Chemistry World November 2010	Carbon Couplers Take the Prize Three giants of organic chemistry, who pioneered palladium-catalysed cross coupling reactions, have shared this year's Nobel prize.
Chemistry World September 29, 2015	Navigating chemical space How big is chemistry? I don't mean how important is it, or how many people do it, but rather, how many molecules are there that we could make?
Chemistry World October 8, 2008 Sarah Houlton	Artificial protein chemistry licensed to industry UK researchers are licensing to industry their method of making artificial proteins by chemically modifying individual amino acid structures.
Chemistry World October 9, 2006 Michael Gross	Miniature Microbicides Researchers have created miniature antimicrobial peptides that contain only four (as opposed to the usual 12-50) amino acid residues combined with a fatty acid.
Chemistry World October 1, 2014 William Bergius	Nitrogen dioxide and ozone: a sinister synergy Air pollution is detrimental to our health, but now scientists in Australia have revealed new mechanistic insight into how particular pollutants interact with the human respiratory tract.
Chemistry World January 14, 2015 Karl Collins	Alkynes reverse reactivity Coupling together thiols and alkynes -- both inherently nucleophilic species -- is a tricky prospect.
Chemistry World October 28, 2014 Derek Lowe	Chemical space is big. Really big. We are not going to run out of interesting and useful structures, and the uses that they could be put to are probably also beyond our imagining. In chemical space, we really do have an effectively endless frontier.
Chemistry World September 2011 Paul Docherty	Column: Totally Synthetic Corey Stephenson of Boston University is an expert a type of reaction called photochemical reduction-oxidation. He has charmed photons into performing many chemical tricks, but one is a photoredox dehalogenation using blue light and a ruthenium bipyridyl catalyst.
Chemistry World September 29, 2014 David Bradley	Pick and mix macromolecules New ways are discovered to piece together pi-functional molecular building blocks to make a wide range of macromolecules.
Chemistry World August 2009 Derek Lowe	Column: In the pipeline The author considers what makes a good looking drug molecule - and how beauty is in the eye of the beholder
Chemistry World October 1, 2013 Eleanor Merritt	New software for creating green solvents Scientists in France have developed a computer-assisted organic synthesis program to design sustainable solvents from bio-based building blocks.
Reactive Reports Issue 60 David Bradley	Mark Leach Interview with the owner of Meta-Synthesis, a company aimed to reveal the inner secrets of chemistry to as wide an audience as possible.
Chemistry World July 3, 2015 Andy Extance	Copper catalysis overcomes double bond trouble Some carbon-carbon double bonds seem too unreactive for synthetic use -- but that's just how chemists in the US are now exploiting them.
Chemistry World September 30, 2014 Kirsty Muirhead	Mirror peptides hitch a lift into the cell Scientists in the US have developed a method for successfully transporting chemotherapeutic d-peptides into the cell cytosol.
Chemistry World June 2008 Sarah Houlton	Breaking the rules The author finds out about some chemical tricks that can give a new drug the best possible odds of success
The Motley Fool May 25, 2007 Brian Orelli	Amylin Sifts for Gold The biotech mines extra value from its compound library. Investors, take note.
Chemistry World March 16, 2014 Simon Hadlington	Short peptides self-assemble into a catalyst Researchers in the US have created catalysts from peptide chains that are only seven amino acids long.
Chemistry World January 2, 2013 Derek Lowe	Fear of the unknown My mental file drawer labelled 'Terrible Reagents I Have Known' is even larger than the one called 'Lunatics I Have Worked With and their Life-Threatening Ideas'. We organic chemists really do work with some terrible chemicals, and it's up to us to keep them from causing havoc.
Chemistry World October 29, 2009 Phillip Broadwith	Two metals are better than one UK chemists have developed reagents that can metallate ethers and ethene at room temperature without them disintegrating.
Reactive Reports December 2006 David Bradley	Dick Wife An interview with the chemical IT scientist and co-founder of SORD, a scientific publishing company that seeks to solve the problem of organizing the myriad of undocumented chemistry and the chaotic mess of the commercial database.
Chemistry World June 11, 2009 James Urquhart	Enzyme-free assembly of DNA-like molecules US scientists have developed a simple peptide nucleic acid system that self-assembles and adapts to new instructions without enzymes.
Chemistry World November 6, 2009 Simon Hadlington	Boron-based compounds inhibit key HIV enzyme Researchers in the Czech Republic have shown that an unusual class of boron-containing compound can inhibit HIV protease, a key enzyme involved in replicating the virus that causes Aids.
Chemistry World April 25, 2013 Andreas Barth	Chemical bibliometrics Counting compounds instead of publications and citations opens new perspectives for data-based scientific discovery and it can complement and stimulate both experimental and theoretical research.
Chemistry World September 24, 2013 Jennifer Newton	Plants and microorganisms are the original synthetic chemists Greg Challis is a professor of chemical biology at the University of Warwick in the UK. Research in the Challis group encompasses the discovery, biosynthesis, bioengineering and mechanism of action of bioactive natural products.
Chemistry World November 26, 2015 Rebecca Trager	Drug firms to share chemical compound libraries Anglo-Swedish pharmaceutical firm AstraZeneca and French drug company Sanofi have agreed to exchange 210,000 chemical compounds from their respective proprietary libraries.
Chemistry World June 16, 2014 James Urquhart	Handshake assembles new emulsions All it takes to make new stable emulsions with tuneable and novel properties is to give a simple mixture of water, solvent and peptide derivatives a quick shake by hand.
Reactive Reports November 2005 David Bradley	Peter Murray-Rust An interview with the scientific software developer, originally a crystallographer with a DPhil from Oxford, on how he is now helping to establish novel software and Web technologies for chemists and other scientists underpinned by the concept of open source.
Reactive Reports Issue 67 David Bradley	Multichannel Microchemical Factory The microchemical factory approach offers a safer and scaleable approach to producing materials from the very smallest quantities to the largest bulk.
Chemistry World November 25, 2014 James Urquhart	Nanomolar chemistry enables 1500 experiments in a single day Chemists have conducted over 1500 chemistry experiments in under a day thanks to a miniaturized, high throughput automation platform they developed for identifying how synthetic molecules react under various conditions.
Food Processing March 2009 Diane Toops	Kraft Foods Global Thinks Outside the Box with Bioactive Ingredients Kraft hires a pharmaceutical company to help it develop functional foods.
Chemistry World June 4, 2008 Lewis Brindley	Peptide printer goes into overdrive Synthesizing arrays of short peptides could soon be as easy as printing them out - thanks to the development of a modified laser printer that uses amino acids instead of colored ink.
Chemistry World August 22, 2014 Derek Lowe	Death of a reagent Anyone who's been practicing organic chemistry for a while can think back to reactions and reagents that were once in far wider use than they are today.
Chemistry World July 26, 2012 Derek Lowe	Screen shots You might not think that the makeup of a compound screening collection could set off many arguments, but there are a few issues there that will do the trick almost every time.