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Chemistry World
July 3, 2015
Andy Extance
Copper catalysis overcomes double bond trouble Some carbon-carbon double bonds seem too unreactive for synthetic use -- but that's just how chemists in the US are now exploiting them. mark for My Articles similar articles
Chemistry World
July 9, 2012
Phillip Broadwith
'Molecular cobra' turns C-H to C=C A reagent developed by US chemists can selectively introduce synthetically useful C=C double bonds into unactivated carbon chains, guided by an activating group attached to a nearby oxygen or nitrogen atom. mark for My Articles similar articles
Chemistry World
November 2, 2015
Batzelladine B Of all the diverse substances that nature produces, the alkaloids -- small molecules containing basic nitrogen -- have had the greatest impact on human history and health. mark for My Articles similar articles
Chemistry World
November 17, 2008
Simon Hadlington
Catalyst flexes for extra control US chemists have developed a new type of catalyst capable of exerting high stereochemical control over olefin metathesis reactions mark for My Articles similar articles
Chemistry World
September 6, 2006
Michael Gross
Selective Shortcut Chemists have developed a simple catalyst that speeds up the synthesis of a chiral protected building block used in many complex syntheses. mark for My Articles similar articles
Chemistry World
December 17, 2009
Simon Hadlington
Single catalyst gives two products from racemic mixture Chemists in the US have demonstrated a remarkable reaction in which a single catalyst can transform a racemic mixture - molecules identical in every way except for their chirality - into two distinct enantiomerically pure products. mark for My Articles similar articles
Chemistry World
August 16, 2009
Tom Bond
Catalyst free carbon-carbon bond formation The method offers an environmentally friendly way to form one of the most important bonds in organic synthesis. mark for My Articles similar articles
Chemistry World
November 25, 2014
James Urquhart
Nanomolar chemistry enables 1500 experiments in a single day Chemists have conducted over 1500 chemistry experiments in under a day thanks to a miniaturized, high throughput automation platform they developed for identifying how synthetic molecules react under various conditions. mark for My Articles similar articles
Chemistry World
March 25, 2011
Simon Hadlington
New synthesis for chiral anticancer compound The promising anticancer compound nutlin-3 is likely to become more widely available to researchers thanks to a new synthetic protocol developed by US chemists. mark for My Articles similar articles
Chemistry World
March 14, 2014
Simon Hadlington
Chemists make headway on C--H activation challenges Jin-Quan Yu's group at the Scripps Research Institute at La Jolla, California, have synthesized a library of synthetic chiral amino acids which could have applications in the pharmaceutical industry. mark for My Articles similar articles
Chemistry World
June 28, 2013
Anthony King
Titanium takes on Haber -- Bosch process The synthesis of ammonia under milder condition, using less energy and fewer resources, has moved a step closer. mark for My Articles similar articles
Chemistry World
February 20, 2012
James Urquhart
Unusual kinetics of catalyst revealed US researchers have elucidated the unusual reaction kinetics of C-H activation by the palladium(II) catalyst (Pd(OAc) 2). mark for My Articles similar articles
Chemistry World
February 21, 2008
Lewis Brindley
Esters Made Easy with Indium Indium is the basis of a novel catalyst designed to make useful cyclic esters. This catalyst could greatly simplify the production of chiral dihydropyranones, important structural elements in many natural products and pharmaceuticals. mark for My Articles similar articles
Chemistry World
January 2, 2013
Paul Docherty
Flueggine A One of the most prolific sources of biologically active natural products is traditional medicines -- whose active components can be exceptionally potent. The Euphorbiaceae family of plants is a productive source of medicinal targets, including the Securinega alkaloids. mark for My Articles similar articles
Chemistry World
January 27, 2010
Simon Hadlington
Fruity route to control asymmetric syntheses Chemists in the UK have discovered a quick, cheap and easy way to make a key sulfide reagent that can mediate the formation of chirally selective molecules needed for complex organic syntheses. mark for My Articles similar articles
Chemistry World
December 9, 2013
Jessica Cocker
Hydrogen breaks strong bonds with brute force A method developed by Leo Lau of Western University in Canada and colleagues can break C -- H bonds without damaging the rest of the molecule. mark for My Articles similar articles
Chemistry World
June 1, 2006
Michael Gross
New Twists on Catalysis Chemists around the world have discovered several new twists to improve the performance of asymmetric catalysts in hydrogenation reactions. mark for My Articles similar articles
Chemistry World
November 28, 2013
Andy Extance
Base metal catalysts strike hydrogenation gold Three teams have shown that chemists need not rely only on expensive and toxic precious metal catalysts for hydrogenation -- they've found complementary alternatives based on cheap, abundant and safer transition metals. mark for My Articles similar articles
Chemistry World
August 2007
Derek Lowe
Opinion: In the Pipeline Process chemists just don't get the credit they deserve. mark for My Articles similar articles
Chemistry World
March 8, 2011
Jon Cartwright
Carbon nanotubes - a boon for chiral catalysts Researchers in China have created a new catalyst that could help in the production of chiral molecules for medical drugs. The catalyst, which consists of platinum nanoparticles encapsulated in carbon nanotubes, is the most active of its type ever reported. mark for My Articles similar articles
Chemistry World
December 16, 2013
Tim Wogan
Calculations predict stable eight nitrogen molecule Nitrogen could form an N 8 molecular crystal at low temperatures, according to density functional theory calculations done by Israeli and US researchers. mark for My Articles similar articles
Chemistry World
December 16, 2011
Kate McAlpine
Radical experiment assesses interstellar nitrogen Radical reactions are challenging to measure at cold temperatures, but an international team of researchers have recently clocked the rate for atomic nitrogen and hydroxyl radicals at 56K. mark for My Articles similar articles
Chemistry World
March 2012
Lead-oriented synthesis Ian Churcher and Alan Nadin call for the development of more robust synthetic tools to improve small molecule survival rates in the perilous journey from lead to drug mark for My Articles similar articles
Chemistry World
December 23, 2015
Karl Collins
Scratching chiral surfaces There are numerous challenges to developing reactions that exploit chiral surfaces, or employ molecular modifiers (ligands) to create a chiral surface environment and control the stereoselectivity of a transformation. mark for My Articles similar articles
Chemistry World
November 28, 2013
Put the chemistry back in medicinal chemistry Today, synthetic skill is valued and appreciated much less in medicinal chemistry than in chemical development, though it is equally important for both. Much of the blame lies with the mismeasurement of productivity. mark for My Articles similar articles
Chemistry World
November 16, 2012
Yuandi Li
(+)-Myrrhanol C made Spanish chemists have completed the stereospecific total synthesis of (+)-myrrhanol C. This compound is a natural triterpene isolated from mastic gum, a substance well known for its medicinal properties as well as use in various cuisines. mark for My Articles similar articles
Chemistry World
June 2010
Paul Docherty
Column: Totally Synthetic Although its chemistry is mature and varied, my use of silicon reagents in my synthetic forays has been limited to a somewhat clumsy use of hydroxyl protecting groups. mark for My Articles similar articles
Chemistry World
July 10, 2013
Karl Collins
An 'Aye' for details Today, using methods developed by masters of their trade, the modern greats of total synthesis demonstrate that almost any molecule can be prepared given time and effort. mark for My Articles similar articles