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Chemistry World
August 1, 2013
James Urquhart |
Total synthesis outshines biotech route to anticancer drug US scientists have developed the first efficient and scalable route for the total synthesis of ingenol -- a plant-derived diterpenoid used to treat precancerous skin legions.   |
Chemistry World
June 11, 2008
James Mitchell Crow |
New Hope for Anticancer Agent The mode of action of a rare natural product with promising cytotoxic activity has been revealed by scientists in the US while a UK group have come up with a particularly efficient chemical synthesis. |
National Gardening
Dan Hickey |
Beneficial Nematodes Are garden insects a problem? These little critters can help |
Reactive Reports
September 2007
David Bradley |
Insecticidal Synthesis The efforts of 40 PhD chemistry students and many others have found a way to construct azadirachtin -- a natural insecticide from the neem tree -- in a total synthesis of 64 individual chemical reaction steps. |
Chemistry World
November 2007
Dylan Stiles |
Column: Bench Monkey Total synthesis is not immune to the vagaries of fickle fashion. |
Chemistry World
February 3, 2015
Phillip Broadwith |
Fatal blast at Indian chemical plant One worker was killed and a further four injured after an explosion at a chemical manufacturing plant operated by chemicals supplier and custom synthesis firm Survival Technologies in Ankleshwar on 20 January. |
National Gardening
Barbara Richardson |
Rid Your Lawn of Mole Crickets Three species of mole crickets were introduced from South America around 1900, and ever since they have been happily chewing on lawns in the southern United States. Steinernema scapterisci, a nematode, is a natural enemy of one of these introduced species, researchers have found. |
National Gardening
Skip Richter |
Marigolds Send Nematodes Packing Marigolds are often cited as a good choice for reducing soil-borne nematodes that feed on plants. However research supporting these claims has been scarce. Now studies at the University of California are beginning to provide some answers. |
Chemistry World
March 2, 2014
Philip Ball |
Worms build waving towers to get out more Worms secrete very long chain unsaturated wax esters to build towers to escape to a new beetle host |
Chemistry World
April 11, 2014 |
The sultan of synthesis Phil Baran is spurring organic chemists to rethink how they make complex compounds, as Mark Peplow discovers |
This Old House
March 27, 2001
Lynn Ocone |
Growing Perfect Tomatoes Treat yourself to one of the true pleasures of summer: your own homegrown tomatoes fresh from the vine... |
Chemistry World
April 2007
Derek Lowe |
Opinion: In the Pipeline Natural products can be ridiculously complicated. The sheer difficulty of the enterprise is traditionally what made pharmaceutical companies hire people who had worked in total synthesis. But, is total synthesis research still worth the effort? |
Chemistry World
November 16, 2012
Yuandi Li |
(+)-Myrrhanol C made Spanish chemists have completed the stereospecific total synthesis of (+)-myrrhanol C. This compound is a natural triterpene isolated from mastic gum, a substance well known for its medicinal properties as well as use in various cuisines. |
Chemistry World
May 2, 2008
Richard Van Noorden |
Synthesis boost for HIV research Hopes for a new type of HIV therapy have been raised by the first chemical synthesis of a scarce plant compound which flushes the virus out of hiding. |
Chemistry World
July 14, 2011
Simon Hadlington |
Natural Products Made Via a Single Parent Molecule Chemists in the US have taken inspiration from nature to devise a new concept for rapidly and efficiently synthesising structurally diverse natural products from a single common precursor. |
Popular Mechanics
August 2008 |
5 Key Uses of Nematodes in Microscopic OR & Beyond With almost as many genes as humans and the ability to repair their nervous system, these roundworms could lead to human treatments for nerve damage. |
Chemistry World
April 9, 2008
Richard Van Noorden |
The shortest recipe for Tamiflu US chemists have published the shortest synthesis to date of oseltamivir (Tamiflu), the anti-influenza drug which is also used to treat bird flu. |
National Gardening
Charlie Nardozzi |
Fall Garden Cover Crops For healthier soil next spring, sow a cover crop this fall... |
| National Gardening |
Maintaining a Vegetable Garden Healthy, vigorous vegetable plants produce the most flavorful and bountiful harvests. Give your garden plants the moisture and nutrients they need, and keep them weeded and harvested for tasty and nutritious crops. |
Chemistry World
May 8, 2014 |
Mandelalide A The recent synthesis of the proposed structure of mandelalide A is a good example of a well-designed route that seamlessly integrates some cutting-edge chemistry. |
Chemistry World
November 27, 2008
Lewis Brindley |
Bryostatin Synthesis Made Simple US chemists have dramatically shortened the synthesis of byrostatin 16, one of a family of natural products that show promising activity against cancer but can't easily be extracted from nature or made artificially. |
AskMen.com
Jacob Franek |
Parasitic Worms Who knew that parasitic worms were so common? Take the necessary precautions outlined here, and you'll most certainly be living worm-free. |
Chemistry World
June 19, 2013
John Hayward |
Science of synthesis workbench edition: water in organic synthesis If a chemist is looking to do chemistry in (or on) water at the bench, Water in organic synthesis by Shu Kobayashi will be their guide. |
Science News
December 22, 2007
Janet Raloff |
Food for Thought: It's Spud Time The United Nations wants more people to appreciate the potato's potential to fight world hunger. |
Chemistry World
February 2011
Paul Docherty |
Column: Totally Synthetic Although most of the natural products I've discussed have had biological activity at the core of the rationale for their synthesis, most organic chemists will admit that an unusual chemical structure is by far the stronger draw. |
Chemistry World
March 25, 2011
Simon Hadlington |
New synthesis for chiral anticancer compound The promising anticancer compound nutlin-3 is likely to become more widely available to researchers thanks to a new synthetic protocol developed by US chemists. |
Chemistry World
August 25, 2011
David Barden |
Rapid Route to Huperzine A US chemists have devised an efficient synthesis of a natural product with great potential as a protectant against chemical warfare agents and in the treatment of Alzheimer's disease. |
Chemistry World
August 2007
Derek Lowe |
Opinion: In the Pipeline Process chemists just don't get the credit they deserve. |
Chemistry World
July 2008
Kevin Rogers |
What future for small molecule therapy? Pharmaceutical companies overlook bench chemists at their peril |
Bio-IT World
August 18, 2004
Kevin Davies |
In Praise of Chemical Diversity How to build better small-molecule libraries. |
Chemistry World
August 2011
Paul Docherty |
Column: Totally Synthetic Yuanhuapin, a fabulously complex member of the daphnane diterpene orthoester class of natural products, bears an astonishing twelve contiguous stereogenic centres around its seven rings (look closely!). |
Chemistry World
January 21, 2013
Michael Parkin |
Flow synthesis for anticancer drug UK chemists have used a combination of flow chemistry methods with solid-supported scavengers and reagents to synthesize the active pharmaceutical ingredient, imatinib, of the anticancer drug Gleevec. |
Chemistry World
November 24, 2011
Elinor Richards |
Blocking cancer's path A concise synthesis of the natural product rasfonin could reignite interest in this molecule as a tool to develop cancer drugs, say scientists from the Netherlands. |
Chemistry World
November 26, 2013
Paul Docherty |
Gone to completion Where is the art of total synthesis headed? |
Chemistry World
January 2012 |
Rising interest in compound bank David Fox argues for the creation of a centralized repository for small molecules to harness research efforts in drug discovery |
