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Chemistry World
March 10, 2006
Dual Organometallics Enhance Zinc Reactivity Chemists have synthesised organometallic compounds that enable zinc to participate in directed metalation of organic substrates. mark for My Articles similar articles
Chemistry World
April 12, 2012
Simon Hadlington
Recruiting electrophiles for organic cross-coupling Chemists in the US have taken an unconventional approach to carbon cross-coupling and in doing so have potentially opened the door to the rapid and efficient synthesis of a wide range of organic compounds. mark for My Articles similar articles
Chemistry World
September 24, 2009
Phillip Broadwith
Carbon can't but tin can US chemists have discovered that distannynes - tin-based analogues of acetylenes - can react reversibly with ethene to make cyclic complexes. mark for My Articles similar articles
Chemistry World
March 2, 2015
Andy Extance
Chemists zinc up 'aromatic' metal cubes Researchers in China and the US have synthesized polyzinc clusters that have pushed back the boundaries of the kind of aromatic structures chemists can make. mark for My Articles similar articles
Chemistry World
November 25, 2014
James Urquhart
Nanomolar chemistry enables 1500 experiments in a single day Chemists have conducted over 1500 chemistry experiments in under a day thanks to a miniaturized, high throughput automation platform they developed for identifying how synthetic molecules react under various conditions. mark for My Articles similar articles
Chemistry World
November 2010
Carbon Couplers Take the Prize Three giants of organic chemistry, who pioneered palladium-catalysed cross coupling reactions, have shared this year's Nobel prize. mark for My Articles similar articles
Chemistry World
December 5, 2012
Phillip Broadwith
Chemical reactions in hot water Chinese and Japanese chemists have highlighted hot water's ability to promote unexpected reactions without any other reagents or catalysts. The work should expand our understanding of how to harness the physicochemical properties of water to potentially replace more complex reagents and catalysts. mark for My Articles similar articles
Chemistry World
November 8, 2007
James Mitchell Crow
First Mg(I) Complex Made Chemists have created the first stable magnesium(I) compounds, a breakthrough for a metal whose chemistry is ruled by the oxidation state. mark for My Articles similar articles
Chemistry World
August 2008
Column: In the pipeline Problems develop when there are too few workhorse reactions, which may well generate compounds that are too similar to each other. Are we at that stage now? mark for My Articles similar articles
Chemistry World
May 29, 2015
Derek Lowe
Magic molecule modifiers The synthesis of a new organic molecule can be approached in several ways. mark for My Articles similar articles
Chemistry World
November 7, 2013
Polly Wilson
Hydrogen adopts alkali metal position For the first time, scientists have shown that hydrogen can stand in for alkali metals in typical alkali metal structures. mark for My Articles similar articles
Chemistry World
October 2009
Column: In the pipeline Derek Lowe discusses the problem of leaning too heavily on favorite reactions mark for My Articles similar articles
Chemistry World
June 2007
Dylan Stiles
Opinion: Bench Monkey This PhD student takes an organic chemist's tour around the periodic table. mark for My Articles similar articles
Chemistry World
March 20, 2007
Tom Westgate
Is Your Lab Ready to go Veggie? In a recently published review article, Geoffrey Cordell demonstrates that the greengrocer's could be an unexpected goldmine of sustainable, cheap reagents that would benefit chemistry in developing countries. mark for My Articles similar articles
Chemistry World
February 6, 2011
Laura Howes
Cells as test tubes Chemists have used living cells as test tubes to carry out chemical reactions never before seen within living cells. mark for My Articles similar articles
Chemistry World
July 8, 2010
Phillip Broadwith
Flattening carbon UK researchers have managed to synthesise a molecule with an almost planar four-coordinate carbon atom bonded to two lithium atoms and bulky organic ligands. mark for My Articles similar articles
Chemistry World
June 2008
Sarah Houlton
Breaking the rules The author finds out about some chemical tricks that can give a new drug the best possible odds of success mark for My Articles similar articles
Reactive Reports
December 2006
David Bradley
Dick Wife An interview with the chemical IT scientist and co-founder of SORD, a scientific publishing company that seeks to solve the problem of organizing the myriad of undocumented chemistry and the chaotic mess of the commercial database. mark for My Articles similar articles
Chemistry World
August 2007
Derek Lowe
Opinion: In the Pipeline Process chemists just don't get the credit they deserve. mark for My Articles similar articles
Chemistry World
April 25, 2014
Derek Lowe
Engineering serendipity At this stage in the world of organic chemistry, you'd have to think that many of the great reactions that can be stumbled across with known reagents have probably been found. mark for My Articles similar articles
Chemistry World
February 2008
Dylan Stiles
Column: Bench Monkey Cast a skeptical eye over new ideas in chemistry. mark for My Articles similar articles
Chemistry World
January 2, 2013
Derek Lowe
Fear of the unknown My mental file drawer labelled 'Terrible Reagents I Have Known' is even larger than the one called 'Lunatics I Have Worked With and their Life-Threatening Ideas'. We organic chemists really do work with some terrible chemicals, and it's up to us to keep them from causing havoc. mark for My Articles similar articles
Chemistry World
January 25, 2013
Derek Lowe
Name reactions: how does the label stick? Some of these names go back to the 19th century, and many more of them come from the first decades of the 20th. Once in a while, I wonder if the tradition is dying out. Are we still naming chemical reactions after their discoverers? mark for My Articles similar articles
Chemistry World
August 2009
Derek Lowe
Column: In the pipeline The author considers what makes a good looking drug molecule - and how beauty is in the eye of the beholder mark for My Articles similar articles
Chemistry World
June 2011
Column: In the pipeline Chemists are human. Humans are hierarchical. Therefore...well, therefore, you'll find a number of different roles and levels for scientists in a drug company's labs. Here's a rough ordering, from least experienced to most. mark for My Articles similar articles
Chemistry World
August 22, 2014
Derek Lowe
Death of a reagent Anyone who's been practicing organic chemistry for a while can think back to reactions and reagents that were once in far wider use than they are today. mark for My Articles similar articles
Chemistry World
November 2007
Derek Lowe
Column: In the Pipeline Chemists are finally going with the flow. mark for My Articles similar articles
Chemistry World
September 26, 2012
Derek Lowe
Under pressure Someone interviewing for a synthetic chemistry position had better know his or her organic chemistry. It's fair to ask questions that will make sure of that. But does a candidate need to know the curly-arrow details of reactions that they'll never run? mark for My Articles similar articles
Chemistry World
March 2012
Column: In the pipeline Drug discovery requires experimentation, says Derek Lowe. But chemists can be reluctant to stray from the elements they know and love mark for My Articles similar articles
Chemistry World
October 2007
Derek Lowe
In the Pipeline One of the biggest areas of chemical research these days is in catalytic processes. It's one of the places we can really improve our processes, especially when you count the waste stream (as you should) as part of the total energy bill. mark for My Articles similar articles
Chemistry World
September 7, 2014
Michael Gross
Bringing chemical synthesis to the masses The promise of a novel approach to building chemical libraries, which only requires simple building blocks in water, without any additional reagents or sample preparation, is inspired by nature. mark for My Articles similar articles
Chemistry World
June 1, 2012
Derek Lowe
Peace, love and understanding You'd think that the chemists and biologists working in drug discovery would understand each other pretty well by now. You would be wrong about that. mark for My Articles similar articles
Chemistry World
October 2008
Derek Lowe
Column: In the pipeline The author seeks a cure for 'compound bloat' mark for My Articles similar articles
Chemistry World
February 7, 2010
Kate McAlpine
Closure on a knotty problem Nine years ago, Chris Hunter's group at the University of Sheffield in the UK reported that they could use a zinc ion to tie an open knot in a linear oligomer. mark for My Articles similar articles
Reactive Reports
Issue 67
David Bradley
Multichannel Microchemical Factory The microchemical factory approach offers a safer and scaleable approach to producing materials from the very smallest quantities to the largest bulk. mark for My Articles similar articles
Chemistry World
January 13, 2011
Sarah Corcoran
Unclogging the problems of flow chemistry US scientists have found a way to stop solid byproducts clogging channels in continuous flow reactors, a problem that has hampered their progress for use in manufacturing pharmaceuticals. mark for My Articles similar articles
Chemistry World
April 2011
Column: In the Pipeline If you look over the whole pharmacopeia, you'll see there are a lot of compounds that got their start as natural products. mark for My Articles similar articles
Chemistry World
October 15, 2012
John Hayward
Oxidizing agents Oxidation in Organic Synthesis by V.K .Ahluwalia contains an extensive list of reagents and is of some interest as a reference resource, particularly with respect to some of the more exotic reagents. mark for My Articles similar articles
Chemistry World
February 15, 2011
Mary Badcock
Building up a natural product toolkit US scientists have come up with a method that makes it easier to extract compounds that are difficult to isolate from crude natural product mixtures. mark for My Articles similar articles
Chemistry World
October 2010
Column: In the pipeline Derek Lowe investigates the comeback combinatorial chemistry has made in the field of drug discovery mark for My Articles similar articles
Chemistry World
July 2, 2014
Victoria Richards
Molecular brass Brass has been known to man since prehistoric times; now scientists in Germany have isolated the first molecular example of the copper -- zinc alloy. mark for My Articles similar articles
Chemistry World
December 10, 2014
Big pharma opens up abandoned drugs Sixty eight stalled pharmaceutical compounds are being made available for academic research through the UK Medical Research Council. mark for My Articles similar articles
Chemistry World
December 2008
Column: In the pipeline I've worked on two drug discovery efforts (one right after the other, as fate would have it) whose final compounds differed by essentially one methyl group from the starting points of each project. mark for My Articles similar articles