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Bio-IT World
September 2006
Kevin Davies
Pfizer's Global Survey of Pharmacological Space The pharma blends knowledge, computational chemistry and research informatics to build a unified database. Gathering all the data in one place offered greater control for indexing and data retrieval and management, enabling Pfizer scientists to perform global mapping. mark for My Articles similar articles
Bio-IT World
May 19, 2004
John Russell
Informatics Black Boxes ... Not! Vertex's chief technical officer, discusses informatics' bad reputation, buying vs. building, open-source tools, and ROI on IT. mark for My Articles similar articles
Chemistry World
August 13, 2015
Exploiting the data mine Chemists must embrace open data to allow us to collectively get the best out of the masses of new knowledge we unearth, reports Clare Sansom mark for My Articles similar articles
Bio-IT World
November 2006
Kevin Davies
Jubilant Curries Favor with BioPharma The explosion of drug discovery and development operations in India is epitomized by the success of several companies. Quietly building on a decade of experience in computational and bio-IT fields, JBL is rapidly pushing into a suite of drug discovery and development activities. mark for My Articles similar articles
Bio-IT World
January 13, 2003
John Dodge
Managing Innovation and Adversity ArQule CIO Alan Hillyard's database migration project became more challenging -- and more important -- following recent layoffs. The good news is that progress continues. mark for My Articles similar articles
Bio-IT World
June 17, 2004
Mark D. Uehling
How to Spell Discovery Rapidly combining cosmos of chemical and biological data, Johnson & Johnson's multidisciplinary ABCD platform for drug discovery aims to give scientists access to more information -- and the ability to make better decisions mark for My Articles similar articles
Bio-IT World
January 21, 2005
Defining 'Integrative Genomics' Five experts from academia and industry discuss the burgeoning field of integrative genomics. mark for My Articles similar articles
Bio-IT World
April 15, 2003
Mark D. Uehling
Target Elimination Industry and FDA scientists turn to databases, applications software, and laboratory chips to move the safest, most effective molecules into clinical trials. mark for My Articles similar articles
Chemistry World
June 2008
Sarah Houlton
Breaking the rules The author finds out about some chemical tricks that can give a new drug the best possible odds of success mark for My Articles similar articles
Chemistry World
September 29, 2015
Navigating chemical space How big is chemistry? I don't mean how important is it, or how many people do it, but rather, how many molecules are there that we could make? mark for My Articles similar articles
Chemistry World
May 22, 2013
Notebooks go digital Electronic lab notebooks are changing the way many scientists interact with information. These notebooks, ELNs for short, capture experiment details and data that are fully searchable within and across experiments. mark for My Articles similar articles
Reactive Reports
Issue 74
David Bradley
Reactive Profile--Noel O'Boyle Interview with a Postdoctoral Research Associate in the Development Group working on drug discovery, protein-ligand docking, cheminformatics, QSAR, and computational chemistry. mark for My Articles similar articles
Chemistry World
March 5, 2015
Emma Stoye
Forgotten synthetic PhD theses set to be given new lease of life A team of researchers have amassed a digital collection of more than 75,000 compounds from PhD theses that might otherwise have mouldered in obscurity. mark for My Articles similar articles
Bio-IT World
December 10, 2002
Arielle Emmett
Locus Focus Cheminformatics company Locus Discovery is a technology darling and an entrepreneur's dream, but it faces a dilemma over how much of its proprietary drug discovery software and data to reveal. mark for My Articles similar articles
Bio-IT World
November 19, 2004
Kevin Davies
De-Lovely Pharmaceuticals De Novo Pharmaceuticals identifies novel compounds right before your eyes. mark for My Articles similar articles
Reactive Reports
Issue 57
Interview with Andrew Lemon With a background in Chemistry and a keen sense of business, this co-found of The Edge Software Consultancy helps global pharmaceutical companies increase the efficiency and productivity of their software tools. mark for My Articles similar articles
CIO
October 15, 2001
Stephanie Overby
Drug Companies on speed The marriage of IT and medical research may be just what traditional pharmaceutical companies need to survive in an increasingly competitive field. Learn how IT is bringing the pharmaceutical industry into the information age... mark for My Articles similar articles
Chemistry World
May 20, 2015
Katrina Kramer
Taking the lead on drug discovery Researchers from the UK have developed a straightforward strategy for making compounds that have the potential to become clinical drugs. mark for My Articles similar articles
Chemistry World
October 2010
Column: In the pipeline Derek Lowe investigates the comeback combinatorial chemistry has made in the field of drug discovery mark for My Articles similar articles
Chemistry World
January 2008
Philip Ball
Column: The Crucible Does chemical space limit a chemists' creativity? mark for My Articles similar articles
Reactive Reports
Issue 55
David Bradley
Interview with Wendy Warr This well-known and well-respected expert in the field of chemical information creates online reports and opinions that are essential reading for chemists hoping to understand the changes in information that are currently underway. mark for My Articles similar articles
ONLINE
Sep/Oct 2007
Svetla Baykoucheva
A New Era in Chemical Information: PubChem, DiscoveryGate, and Chemistry Central How the emergence of PubChem, DiscoveryGate and Chemistry Central are changing the field of chemical information. mark for My Articles similar articles
Chemistry World
December 2008
Column: In the pipeline I've worked on two drug discovery efforts (one right after the other, as fate would have it) whose final compounds differed by essentially one methyl group from the starting points of each project. mark for My Articles similar articles
Chemistry World
December 2007
Richard Van Noorden
Surfing Web2O The rapid evolution of the world wide web is creating fresh opportunities - and challenges - for chemistry. mark for My Articles similar articles
Chemistry World
August 2007
Derek Lowe
Opinion: In the Pipeline Process chemists just don't get the credit they deserve. mark for My Articles similar articles
Bio-IT World
February 10, 2003
Malorye Branca
Conquering Infinity with Chemical Genetics Harvard superchemist Stuart Schreiber defines the convergence of chemistry and biology. Now the field of chemical genetics is heading toward the clinic. mark for My Articles similar articles
Bio-IT World
September 2006
Mike May
Working Out the Flow Better management of workflow issues in biotech and pharma could change fundamental aspects of these sciences in the near future. mark for My Articles similar articles
Reactive Reports
November 2005
David Bradley
Peter Murray-Rust An interview with the scientific software developer, originally a crystallographer with a DPhil from Oxford, on how he is now helping to establish novel software and Web technologies for chemists and other scientists underpinned by the concept of open source. mark for My Articles similar articles
Chemistry World
October 2008
Derek Lowe
Column: In the pipeline The author seeks a cure for 'compound bloat' mark for My Articles similar articles
Chemistry World
November 28, 2013
Put the chemistry back in medicinal chemistry Today, synthetic skill is valued and appreciated much less in medicinal chemistry than in chemical development, though it is equally important for both. Much of the blame lies with the mismeasurement of productivity. mark for My Articles similar articles
Bio-IT World
June 17, 2004
John Garvey
Rational Decisions As companies in the computationally guided rational drug design sector mature, they should be more sure of the boundaries that surround their proprietary technologies. mark for My Articles similar articles
Chemistry World
December 16, 2013
Anthony King
Database of 15 million chemical structures set free A collection of over 15 million chemical structures from patents -- SureChem -- is to be made freely available through the European Bioinformatics Institute. mark for My Articles similar articles
Chemistry World
April 25, 2013
Andreas Barth
Chemical bibliometrics Counting compounds instead of publications and citations opens new perspectives for data-based scientific discovery and it can complement and stimulate both experimental and theoretical research. mark for My Articles similar articles
Bio-IT World
October 14, 2004
Salvatore Salamone
Riding the New Wave New offerings from Accelrys, LION bioscience, MDL, Synthematix, and Tripos may be the crest of a new wave of software designed to meet increasing demand to incorporate chemoinformatics into the drug discovery process. mark for My Articles similar articles
Chemistry World
April 2011
Molecular Obesity is Weighing Down Drug Discovery Medicinal chemistry's quest for potent drug candidates has resulted in molecules that are too large and too lipophilic for their own good. mark for My Articles similar articles
Bio-IT World
August 18, 2004
Kevin Davies
In Praise of Chemical Diversity How to build better small-molecule libraries. mark for My Articles similar articles
Bio-IT World
Dec 2006/Jan 2007
Giacomo Bastianelli
The Future of Predictive Biology Predictive biology, data and the integration of disparate research disciplines are key ingredients for the future of drug discovery research and healthcare. mark for My Articles similar articles
Chemistry World
December 2010
A structure-based community for chemists ChemSpider, a free online database of chemicals and related information, has delivered an online environment for the community to both deposit their data as well as curate and annotate existing content on the database. mark for My Articles similar articles
Bio-IT World
April 16, 2004
Malorye Branca
Finding the Perfect Fit Fragment-based drug discovery is unique and effective. mark for My Articles similar articles
Chemistry World
June 1, 2012
Derek Lowe
Peace, love and understanding You'd think that the chemists and biologists working in drug discovery would understand each other pretty well by now. You would be wrong about that. mark for My Articles similar articles
Chemistry World
February 8, 2006
Jon Evans
To Boldly go Where no Chemist Has Gone Before Studying the interactions between different molecular fragments is taking researchers to the uncharted regions of chemical space. mark for My Articles similar articles
Chemistry World
November 25, 2014
James Urquhart
Nanomolar chemistry enables 1500 experiments in a single day Chemists have conducted over 1500 chemistry experiments in under a day thanks to a miniaturized, high throughput automation platform they developed for identifying how synthetic molecules react under various conditions. mark for My Articles similar articles
Bio-IT World
November 12, 2002
James Golden
The Business of Bioinformatics The industry has reached an interesting crossroads. As an academic branch of learning, bioinformatics remains mostly what it always was, a cross-disciplinary endeavor between computer science and molecular biology. But bioinformatics as a money-making proposition has different criteria for success. mark for My Articles similar articles
Reactive Reports
December 2006
David Bradley
Dick Wife An interview with the chemical IT scientist and co-founder of SORD, a scientific publishing company that seeks to solve the problem of organizing the myriad of undocumented chemistry and the chaotic mess of the commercial database. mark for My Articles similar articles
Chemistry World
May 2010
Mobile chemistry - chemistry in your hands and in your face Mobile chemistry has arrived. This short article will review some of the available tools and offers a view of what the near term future may hold for this domain. mark for My Articles similar articles
Chemistry World
March 2012
Lead-oriented synthesis Ian Churcher and Alan Nadin call for the development of more robust synthetic tools to improve small molecule survival rates in the perilous journey from lead to drug mark for My Articles similar articles
Information Today
May 5, 2011
Robert E. Buntrock
SciPlanner: Latest Addition to the CAS Suite of Programs In over a century of existence, Chemical Abstract Service has become the premier source of chemical information. mark for My Articles similar articles
Chemistry World
November 30, 2012
Andy Extance
Chemists cull compounds using 'intuition' Medicinal chemists might be using far fewer parameters to choose candidate fragments for a screening collection than they think they do. Their choices can be mimicked based on just one or two properties, a team led by researchers at Swiss-headquarted pharmaceutical firm Novartis has found. mark for My Articles similar articles
Chemistry World
July 2008
Kevin Rogers
What future for small molecule therapy? Pharmaceutical companies overlook bench chemists at their peril mark for My Articles similar articles
HHMI Bulletin
Nov 2011
Sarah C. P. Williams
Living Chemistry Biologists understand better what chemists can bring to the table. And chemists understand better the questions that biologists really care about. This has led to a bigger impact of chemists on biological problems. mark for My Articles similar articles