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Bio-IT World
January 21, 2005
Defining 'Integrative Genomics' Five experts from academia and industry discuss the burgeoning field of integrative genomics. mark for My Articles similar articles
Bio-IT World
November 2006
Robert M. Frederickson
Managing Data on the Go GeneGo has created a suite of software and database products that aim to facilitate analysis of the biology behind different types of high-throughput experimentation and understand the effects of small molecule drug compounds in human tissues. mark for My Articles similar articles
Bio-IT World
July 2005
David M. Evans
Cellular Imaging Takes Drug Discovery to New Heights The potential applications and ultimate value of high-content screening (HCS) and cellular image analysis are limited only by the imagination and expertise of the drug discovery groups using them to probe gene function and cell behavior. mark for My Articles similar articles
Bio-IT World
February 10, 2003
Malorye Branca
Conquering Infinity with Chemical Genetics Harvard superchemist Stuart Schreiber defines the convergence of chemistry and biology. Now the field of chemical genetics is heading toward the clinic. mark for My Articles similar articles
Bio-IT World
Jul/Aug 2006
Deb Janssen
Managing the Microarray Data Mountain Genomic studies often involve thousands of samples and require hundreds of thousands of assays per sample. Microarray manufacturers are scurrying to satisfy researcher demands for increased array density, sample number, and content flexibility. mark for My Articles similar articles
Industrial Physicist
Jennifer Ouellette
Bioinformatics moves into the mainstream An explosion of data is being tamed with new systems mark for My Articles similar articles
CIO
October 15, 2001
Stephanie Overby
Drug Companies on speed The marriage of IT and medical research may be just what traditional pharmaceutical companies need to survive in an increasingly competitive field. Learn how IT is bringing the pharmaceutical industry into the information age... mark for My Articles similar articles
Bio-IT World
December 15, 2003
Zachary Zimmerman
Learning the Language of Systems Biology Geneticist par excellence David Botstein talks about his philosophy, science, his mission for integrative science, and what he deems a success for systems biology. mark for My Articles similar articles
Pharmaceutical Executive
February 1, 2006
Ron Feemster
Gene Logic: Rescue Squad One or two late-stage clinical failures can land promising drug candidates on the shelf. Forever? Maybe not. Gene Logic tests Big Pharma's dead drugs for hundreds of different targets. mark for My Articles similar articles
Bio-IT World
May 9, 2003
Vivien Marx
The Sharper Image See it, capture it, mine it, find it. The budding field of image informatics is empowering biomedical research. mark for My Articles similar articles
Bio-IT World
July 11, 2002
Malorye Branca
Deep Sequence Diving Like sailors of old, genomic data miners dream of discovering riches and fame. Given the recent improvements in analytics -- and a little more time -- they just might succeed. mark for My Articles similar articles
Bio-IT World
July 14, 2004
Malorye A. Branca
The Pathways Promise By using the right tools, even a modest genomic data set can generate a good view into a particular biological pathway. Now, a range of new technologies is arising from academia as well as the commercial sector to meet this need. mark for My Articles similar articles
Bio-IT World
April 15, 2003
Mark D. Uehling
Target Elimination Industry and FDA scientists turn to databases, applications software, and laboratory chips to move the safest, most effective molecules into clinical trials. mark for My Articles similar articles
Bio-IT World
December 15, 2003
Malorye A. Branca
Scenes from a Cell Breakthroughs are making cell-based screening faster, easier, more powerful. mark for My Articles similar articles
Bio-IT World
November 14, 2003
Jeff Augen
Making Information-Based Medicine Work A confluence of scientific discovery and high-throughput technology has made information-based medicine possible -- and imperative. mark for My Articles similar articles
Bio-IT World
May 19, 2004
John Russell
Informatics Black Boxes ... Not! Vertex's chief technical officer, discusses informatics' bad reputation, buying vs. building, open-source tools, and ROI on IT. mark for My Articles similar articles
Bio-IT World
September 2006
Mike May
Working Out the Flow Better management of workflow issues in biotech and pharma could change fundamental aspects of these sciences in the near future. mark for My Articles similar articles
Bio-IT World
September 2006
John A. Wass
Integrating Knowledge The results of new mathematical routines have the potential to save pharmaceuticals millions of dollars in drug development. And yet the flow of successful drugs is dwindling. The problem goes beyond bureaucracy and lies in the complexity of the problem. mark for My Articles similar articles
Bio-IT World
June 2006
Kevin Davies
The Data Deluge: Deal or No Deal? Far from decrying the data glut, researchers should embrace the complexity of genomic and other sources of data, particularly for its predictive properties in the field of personalized medicine. mark for My Articles similar articles
Bio-IT World
November 12, 2002
James Golden
The Business of Bioinformatics The industry has reached an interesting crossroads. As an academic branch of learning, bioinformatics remains mostly what it always was, a cross-disciplinary endeavor between computer science and molecular biology. But bioinformatics as a money-making proposition has different criteria for success. mark for My Articles similar articles
Bio-IT World
March 10, 2003
Mark D. Uehling
Technology Overload Inundated with new IT tools and mountains of data, the pharmaceutical industry struggles to pull it all together. mark for My Articles similar articles
Bio-IT World
October 10, 2003
Donna Mendrick
Microarrays That Make Drugs Safe Using DNA chips to discover potential toxicity in new drug compounds -- a key application of toxicogenomics -- can predict adverse effects before they occur, enabling safer clinical trials. mark for My Articles similar articles
Bio-IT World
January 21, 2005
Salvatore Salamone
A Prescription for Information-Based Medicine TurboWorx president and CEO Jeff Augen not only combines computational and biology expertise, but also has a clear vision of how to advance life science discovery. mark for My Articles similar articles
Salon.com
May 1, 2000
Arthur Allen
Listening to DNA The genome project is getting the buzz. But the real breakthroughs may come from labs out of the limelight, like Gene Logic. mark for My Articles similar articles
Bio-IT World
September 16, 2004
Michael A. Greeley
Platforms for Pathways Investor interest in the next great blockbuster drug has been blistering hot; Phase II and Phase III compound companies are being funded at a near record-breaking pace now that the IPO window seems to be slightly open mark for My Articles similar articles
Pharmaceutical Executive
July 1, 2005
Zaborowski, Hammer & Lawler
Informatics Rules How global computer systems helped far-flung research centers at Roche work together mark for My Articles similar articles
Bio-IT World
November 2006
Kevin Davies
Compute for the Cure Computational comparison offers a seductive new approach to identify new drugs for disease, as well as re-purposing existing drugs. mark for My Articles similar articles
Bio-IT World
February 10, 2003
Salvatore Salamone
Made in Manhattan A talk with the new head of the Computational Biology Center at Memorial Sloan-Kettering. mark for My Articles similar articles
Bio-IT World
September 9, 2002
John P. Helfrich
Data Management in High-Throughput Screening The high-throughput drug discovery field requires an optimal IT platform. mark for My Articles similar articles
Bio-IT World
March 10, 2003
Richard Dweck
Sifting Through Standards Standards in informatics can sometimes raise more questions than they answer. Take a pragmatic approach. mark for My Articles similar articles
Bio-IT World
October 10, 2003
Mark D. Uehling
Digging Into Digital Quarries Industrial-strength software is helping discover unexpected connections in the scientific literature. mark for My Articles similar articles
Industrial Physicist
Apr/May 2003
Jennifer Oullette
Switching from physics to biology Physicists in transition help shape biological theory. mark for My Articles similar articles
Bio-IT World
November 2006
Kevin Davies
Building a Bridge Over Pharma with IT More than 100 enthusiastic delegates bridging the full breadth of the drug development pipeline gathered recently for the second annual Bridging Pharma and IT conference. Here are some highlights. mark for My Articles similar articles
Bio-IT World
September 2006
John Russell
Informatics Cornucopia Predictive Informatics, the hopeful title of a session at last month's Drug Discovery Technology & Development World Congress, remains an enticing but mostly elusive goal. Asked what systems biology would look in five years and what will constitute success, panelists offered the following. mark for My Articles similar articles
Bio-IT World
June 12, 2002
Beth Schachter
Informatics Moves to the Head of the Class The race is on to increase the quantity and quality of bio-IT training programs as government and academia bet the need will be great. Will the job market back up that bet? mark for My Articles similar articles
Bio-IT World
April 2007
Leach & Tedeschi
If THEY Build It, THEY Will Come Biopharma companies have many lessons to learn from the emerging and maturing Web 2.0 technologies. While social networking will help foster the exchange of ideas, sharing data remains one of the biopharma industry's greatest challenges. mark for My Articles similar articles
Bio-IT World
February 18, 2004
Proteomics Goes Cellular Tissue microarrays save big on sample material and reagents. But more importantly, this new high-throughput technology is helping save the lives of cancer patients mark for My Articles similar articles
Bio-IT World
September 9, 2002
Letters Frustrated in Gene Town... IT for the Biologists, by the Biologists?... mark for My Articles similar articles
Bio-IT World
July 11, 2002
Stephen T.C. Wong
Neuro-IT Needs Integrated Infrastructure There are two major motivations for merging enterprise solutions into clinical neuroscience. The first is the need to scale up the capacity for data management. The second is the economic benefits of data sharing, software reuse, and infrastructure build-out while reducing costs. mark for My Articles similar articles
Bio-IT World
October 9, 2002
Malorye Branca
The Path to Personalized Medicine The tactics have changed, sometimes dramatically, but hints of the promise of pharmacogenomics are finally starting to trickle in from studies of asthma, cancer, and drug response. mark for My Articles similar articles
Bio-IT World
May 7, 2002
Malorye Branca
In Silico Survivors Facing desperate times, bioinformatics companies revamp, refocus, or perish. mark for My Articles similar articles
HHMI Bulletin
Aug 2010
Sarah C.P. Williams
Fruit Fly Cells Don't All Know What Sex They Are HHMI scientists have now found that many cells in male and female fruit flies not only look the same, they are more identical at a molecular level than was previously thought. mark for My Articles similar articles
Bio-IT World
November 2005
Bridges and Boundaries in Drug Discovery Research Good communication, blurring cultural boundaries, and strong project governance may be as, if not more, important as sweeping technology solutions when it comes to converging discovery and IT and expediting drug development. mark for My Articles similar articles
Bio-IT World
September 2006
Nat Goodman
Getting a Handle on Systems Biology Systems biology is squarely an experimental field that eats, drinks, and breathes data. To do systems biology, you need an experimental system that is amenable to large-scale experimentation. mark for My Articles similar articles
Bio-IT World
June 17, 2004
John Russell
Systems Biology - Now Leaving on Track 1 Entelos, a leader in predictive biosimulation, partners with pharmaceutical and biotech organizations worldwide to develop effective new treatments for disease. Michael French, chief business officer at Entelos, explains what powers the systems biology engine. mark for My Articles similar articles
Bio-IT World
December 15, 2004
William Marshall
Applications of RNAi RNA interference is a highly coordinated gene regulatory mechanism that appears to be highly conserved across all metazoans studied thus far. mark for My Articles similar articles
Bio-IT World
October 14, 2004
William Pulleyblank
Rewriting the Rulebook for Supercomputing and Research IBM's Blue Gene supercomputer project leader highlights progress and future applications. mark for My Articles similar articles
Bio-IT World
April 2007
Vicki Glaser
Software Solutions for Medicinal Chemistry Driven by advances in chemical synthesis, instrumentation, and high-throughput and high-content screening technology, medicinal chemistry's transition from an art to a science is benefiting from a wealth of new software products, spanning both bio- and cheminformatics. mark for My Articles similar articles
Bio-IT World
March 10, 2003
Salvatore Salamone
Common Knowledge Two heads (or more) are better than one, except when they don't share information. That's where knowledge management comes in. mark for My Articles similar articles
Chemistry World
May 17, 2006
Bea Perks
Biochemists Reveal Hidden Drug Effects Researchers have identified unexpected drug activities by probing biochemical pathways inside living cells. mark for My Articles similar articles