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Bio-IT World
February 2006
John Russell
Marvelous Models of Biological Systems Here are highlights from a roundtable discussion with researchers representing academia and pharmaceuticals, as well as executives from modeling technology providers on whether or not Pharma is ready to bet on computational modeling of biological systems. mark for My Articles similar articles
Bio-IT World
Dec 2006/Jan 2007
John Russell
Setting the Systems Bio Syllabus An interview with David de Graaf about Pfizer's growing comfort with systems biology. mark for My Articles similar articles
Bio-IT World
June 17, 2004
John Russell
Systems Biology - Now Leaving on Track 1 Entelos, a leader in predictive biosimulation, partners with pharmaceutical and biotech organizations worldwide to develop effective new treatments for disease. Michael French, chief business officer at Entelos, explains what powers the systems biology engine. mark for My Articles similar articles
Bio-IT World
September 2006
John Russell
Predicting the Future of Systems Biology Buoyed by promising results from a recent collaboration with Pfizer on drug-induced vascular injury, Keith Elliston, CEO of modeling and biosimulation specialist Genstruct, offers a candid view of industry's flirtation with systems biology and the future prospects for the field. mark for My Articles similar articles
Bio-IT World
November 12, 2002
Michael Goldman
A Virtual Pharmacopeia Computational modeling of disease pathways, organs --- even patients --- could transform drug discovery. Does salvation exist in silico? mark for My Articles similar articles
Bio-IT World
May 19, 2004
John Russell
Seeing the Forest and the Trees A tiny clearing in the fog of systems biology. mark for My Articles similar articles
Bio-IT World
September 2006
Nat Goodman
Getting a Handle on Systems Biology Systems biology is squarely an experimental field that eats, drinks, and breathes data. To do systems biology, you need an experimental system that is amenable to large-scale experimentation. mark for My Articles similar articles
Bio-IT World
February 10, 2003
Salvatore Salamone
Made in Manhattan A talk with the new head of the Computational Biology Center at Memorial Sloan-Kettering. mark for My Articles similar articles
Bio-IT World
January 21, 2005
Defining 'Integrative Genomics' Five experts from academia and industry discuss the burgeoning field of integrative genomics. mark for My Articles similar articles
Industrial Physicist
Jennifer Ouellette
Bioinformatics moves into the mainstream An explosion of data is being tamed with new systems mark for My Articles similar articles
Bio-IT World
June 12, 2002
John Dodge
All Systems Go at ISB The Seattle-based Institute for Systems Biology (ISB), takes a holistic view of genomic and proteomic research. The author spoke with its president, noted biologist Leroy Hood, recently to find out how far ISB has come in its two years of life. mark for My Articles similar articles
Chemistry World Fishing for Chemical Answers to Biological Questions James K. Chen talks about chemical biology, his love for the outdoors and fly fishing. mark for My Articles similar articles
Bio-IT World
March 8, 2005
John Russell
Entelos' Lofty Aspirations This is an interesting period for systems biology's wing of predictive biology companies. The label's luster is fading, but buoyed by pharma's growing interest, they are trying to figure out how to grow. mark for My Articles similar articles
HHMI Bulletin
Nov 2011
Sarah C.P. Williams.
Carolyn Bertozzi: Changed Expectations Chemists trained in biology were once a rarity -- now they're becoming the norm. mark for My Articles similar articles
Bio-IT World
November 2005
Bridges and Boundaries in Drug Discovery Research Good communication, blurring cultural boundaries, and strong project governance may be as, if not more, important as sweeping technology solutions when it comes to converging discovery and IT and expediting drug development. mark for My Articles similar articles
Bio-IT World
Dec 2006/Jan 2007
John Russell
Novartis' Answer to Harry Potter Imagine a magic wand able to instantly materialize novel, safe, and effective drugs. No such device exists, of course, but Novartis has a distant cousin of sorts: the UltraLink is an immensely powerful text-mining tool and knowledge management platform. mark for My Articles similar articles
Bio-IT World
July 11, 2002
Malorye Branca
Deep Sequence Diving Like sailors of old, genomic data miners dream of discovering riches and fame. Given the recent improvements in analytics -- and a little more time -- they just might succeed. mark for My Articles similar articles
Bio-IT World
September 2006
Kevin Davies
Pfizer's Global Survey of Pharmacological Space The pharma blends knowledge, computational chemistry and research informatics to build a unified database. Gathering all the data in one place offered greater control for indexing and data retrieval and management, enabling Pfizer scientists to perform global mapping. mark for My Articles similar articles
Bio-IT World
November 12, 2002
James Golden
The Business of Bioinformatics The industry has reached an interesting crossroads. As an academic branch of learning, bioinformatics remains mostly what it always was, a cross-disciplinary endeavor between computer science and molecular biology. But bioinformatics as a money-making proposition has different criteria for success. mark for My Articles similar articles
Bio-IT World
March 8, 2005
John Russell
Debating Business Models for Bioinformatics Companies Nailing down a single formula for successfully selling bioinformatics products or services has proven elusive. Harvard Business School tackles informatics' basic question: Where's the money? mark for My Articles similar articles
Bio-IT World
December 15, 2003
Zachary Zimmerman
Learning the Language of Systems Biology Geneticist par excellence David Botstein talks about his philosophy, science, his mission for integrative science, and what he deems a success for systems biology. mark for My Articles similar articles
Bio-IT World
November 2006
Robert M. Frederickson
Managing Data on the Go GeneGo has created a suite of software and database products that aim to facilitate analysis of the biology behind different types of high-throughput experimentation and understand the effects of small molecule drug compounds in human tissues. mark for My Articles similar articles
Chemistry World
September 13, 2012
Andy Merritt
Chemical biology comes of age Historically strongest in the US, chemical biology has become increasingly important worldwide, but for many years researchers at the chemistry -- biology interface have struggled to establish their discipline mark for My Articles similar articles
Bio-IT World
October 2006
John Russell
GNS Charts "Unknown" Biology Gene Network Sciences' CEO and colleagues now think they have the right tool to mine the treasure trove of unknown biology hidden in the wealth of accumulating omic data. mark for My Articles similar articles
Bio-IT World
August 13, 2002
Russell & Dodge
Necessary Liaisons: Making Standards Work Caroline Kovac, IBM Corp.'s general manager for life sciences, talks about the need for standards and her take on the troubled informatics world. mark for My Articles similar articles
Bio-IT World
July 14, 2004
Malorye A. Branca
The Pathways Promise By using the right tools, even a modest genomic data set can generate a good view into a particular biological pathway. Now, a range of new technologies is arising from academia as well as the commercial sector to meet this need. mark for My Articles similar articles
Bio-IT World
February 2007
Bio*IT World's Coming Attractions 2007 Bio-IT World Conference & Expo preview -- Meet the Keynotes... Oracle Users... Systems are Go... Candid Camera... A Vital IT Alliance... Next Generation Informatics... etc. mark for My Articles similar articles
Knowledge@Wharton A New Approach to Valuing Biotech Stocks Enormous swings in biotechnology stock prices during the last few weeks show how difficult it is for investors to value biotech companies. It's important to understand the invisible potential locked up in the organizational structure of biotechnology companies... mark for My Articles similar articles
Industrial Physicist
Apr/May 2003
Jennifer Oullette
Switching from physics to biology Physicists in transition help shape biological theory. mark for My Articles similar articles
Bio-IT World
June 12, 2002
Beth Schachter
Informatics Moves to the Head of the Class The race is on to increase the quantity and quality of bio-IT training programs as government and academia bet the need will be great. Will the job market back up that bet? mark for My Articles similar articles
Bio-IT World
Jul/Aug 2006
John Russell
MathWorks Launches a 'Systems Biology' Tool The maker of the popular MATLAB programming environment recently launched a modeling product, SimBiology, aimed at systems biology and synthetic biology markets. mark for My Articles similar articles
CIO
October 15, 2001
Stephanie Overby
Drug Companies on speed The marriage of IT and medical research may be just what traditional pharmaceutical companies need to survive in an increasingly competitive field. Learn how IT is bringing the pharmaceutical industry into the information age... mark for My Articles similar articles
Bio-IT World
February 2006
John Russell
Preventable Vioxx Problems? Pathway analysis tools might have identified Vioxx's problematic off-target activity much earlier. Wondering which modeling approach to use for your project? mark for My Articles similar articles
Bio-IT World
May 2006
John Russell
Buyers Panel: What Biopharma Wants What does big (and at least one little) biopharma really want from technology providers? That was the theme of an entertaining session at Bio-IT World's Expo, featuring top IT and informatics executives from Merck, Lilly, Pfizer, Novartis, and Infinity Pharmaceuticals. mark for My Articles similar articles
Chemistry World
January 2012
Cultivating collaboration A new network aims to bring the power of interdisciplinary innovation to bear on global food issues. mark for My Articles similar articles
Bio-IT World
March 2007
John Russell
In Search of Spring Tired of winter? Here are some signs of spring for systems biology acceptance and a preview of Cambridge Healthtech's June conference, Applying Systems Biology, to whet your appetite for summer: 1. FDA Survey... etc. mark for My Articles similar articles
Bio-IT World
May 19, 2004
John Russell
Informatics Black Boxes ... Not! Vertex's chief technical officer, discusses informatics' bad reputation, buying vs. building, open-source tools, and ROI on IT. mark for My Articles similar articles
Bio-IT World
March 17, 2004
Systems Biology: Top-Down or Bottom-Up? Systems biology involves the representation and analysis of an intact biological system. Like many of the technological developments over the past 20 years, such as genomics, proteomics, combinatorial chemistry, and bioinformatics, pharma and medical communities hold high hopes that systems biology will help move molecular research closer to the practice of medicine. mark for My Articles similar articles
Bio-IT World
January 12, 2004
Julia Boguslavsky
New Year Tools for the 'New' Biology Instrumentation outlook for systems biology. mark for My Articles similar articles
Bio-IT World
May 9, 2003
Vivien Marx
The Sharper Image See it, capture it, mine it, find it. The budding field of image informatics is empowering biomedical research. mark for My Articles similar articles
Bio-IT World
January 13, 2003
John Dodge
Talent Fuels Drug Pipeline in Swiss Time The functional genomics group has emerged as a critical link in the drug discovery chain at Novartis Pharmaceuticals Corp. While it employs a multidisciplinary approach to drug discovery, the four-year-old group's goals could not be simpler: Find novel drug targets. mark for My Articles similar articles
Bio-IT World
July 2005
John Russell
Harvard Tackles Systems Biology Towards the end of this summer, researchers at the Virtual Cell Program expect to unleash b -- pronounced "little b" -- a new open-source computer language they hope will energize the biological modeling community as nothing has before. mark for My Articles similar articles
Bio-IT World
October 14, 2004
Deciphering Genstruct If you divide the systems biology world into two broad camps, wet-lab-focused data generators and in silico model makers, Genstruct is a modeler with a twist. mark for My Articles similar articles
Bio-IT World
September 16, 2004
Michael A. Greeley
Platforms for Pathways Investor interest in the next great blockbuster drug has been blistering hot; Phase II and Phase III compound companies are being funded at a near record-breaking pace now that the IPO window seems to be slightly open mark for My Articles similar articles
Wired
August 2004
Oliver Morton
A Machine With a Mind of Its Own Ross King wanted a research assistant who would work 24/7 without sleep or food. So he built one. King's robot can look at the results of a biology experiment, draw a conclusion about what the results might mean, and then set off to test that conclusion. mark for My Articles similar articles
Bio-IT World
April 2007
John Russell
Toward a Cancer Interactome Researchers at the Center for Cancer Systems Biology are working toward identifying the high level wiring diagram for cancer. In this instance, that means an accurate map of all cancer-associated protein-protein interactions. mark for My Articles similar articles
Bio-IT World
April 2006
John Russell
Pfizer's Pursuit of Technology Can this $50-billion-plus, 115,000-employee behemoth succeed where other pharma giants have failed and successfully institutionalize the effort to find and develop critical new technology? Should it even try? mark for My Articles similar articles
Bio-IT World
Dec 2006/Jan 2007
Resolute in the New Year Industry leaders in areas from pharmacogenetics to cheminformatics found 2006 to be a year of important steps forward, but looked with even more anticipation to 2007: Allen D. Roses, SVP, Pharmacogenetics GlaxoSmithKline... etc. mark for My Articles similar articles
Pharmaceutical Executive
July 1, 2005
Zaborowski, Hammer & Lawler
Informatics Rules How global computer systems helped far-flung research centers at Roche work together mark for My Articles similar articles
Bio-IT World
September 2006
Mike May
Working Out the Flow Better management of workflow issues in biotech and pharma could change fundamental aspects of these sciences in the near future. mark for My Articles similar articles