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Bio-IT World May 19, 2004 John Russell |
Informatics Black Boxes ... Not! Vertex's chief technical officer, discusses informatics' bad reputation, buying vs. building, open-source tools, and ROI on IT.  |
Bio-IT World November 12, 2002 James Golden |
The Business of Bioinformatics The industry has reached an interesting crossroads. As an academic branch of learning, bioinformatics remains mostly what it always was, a cross-disciplinary endeavor between computer science and molecular biology. But bioinformatics as a money-making proposition has different criteria for success.  |
Bio-IT World May 19, 2004 Malorye Branca |
Attack of the Lab-Bots Robots are invading every aspect of discovery and development within pharmaceutical companies, from genotyping to high-throughput screening.  |
Pharmaceutical Executive July 1, 2005 Zaborowski, Hammer & Lawler |
Informatics Rules How global computer systems helped far-flung research centers at Roche work together  |
Bio-IT World March 10, 2003 Mark D. Uehling |
Technology Overload Inundated with new IT tools and mountains of data, the pharmaceutical industry struggles to pull it all together.  |
Bio-IT World May 19, 2004 Julia Boguslavsky |
Is Microfluidics Equipped for HTS? As microfluidics technologies mature and increase in throughput, they are starting to offer a highly accurate, flexible, and economical alternative to conventional high-throughput screening (HTS) platforms.  |
CIO October 15, 2001 Stephanie Overby |
Drug Companies on speed The marriage of IT and medical research may be just what traditional pharmaceutical companies need to survive in an increasingly competitive field. Learn how IT is bringing the pharmaceutical industry into the information age...  |
Chemistry World April 14, 2011 Sarah Farley |
Fish in chips: growing embryos in microfluidic systems Scientists in the Netherlands and the UK have shown for the first time that an animal embryo can develop in a microfluidic environment.  |
Pharmaceutical Executive May 1, 2001 |
On Tour with Merck's Robots Merck's HTS robots move assay plates through the screening process.  |
Bio-IT World September 11, 2003 Julia Boguslavsky |
Cellular Screening in Sync No longer just a 'good idea,' high-content cellular screening is making an impact in target and lead selection.  |
Bio-IT World March 2006 Robert M. Frederickson |
Integration, Robotics, and Automation The integration of instruments and technology is a key concept driving the development of advanced life-sciences laboratory automation. More sophisticated robotics are also increasingly being integrated into automated systems.  |
Bio-IT World February 2007 Mike May |
No Limits: The New Look of LIMS As vendors and scientists work towards standardized data formats and improving the tracking of research and results worldwide, laboratory information management systems can pull increasingly more complex sources of information into managing knowledge.  |
Bio-IT World September 2006 Mike May |
Working Out the Flow Better management of workflow issues in biotech and pharma could change fundamental aspects of these sciences in the near future.  |
Chemistry World January 2010 Derek Lowe |
Column: In the pipeline I've recently marked my 20th year of drug discovery research, which prompted me to think about what has changed since I started work in the industry.  |
Bio-IT World April 2007 Vicki Glaser |
Software Solutions for Medicinal Chemistry Driven by advances in chemical synthesis, instrumentation, and high-throughput and high-content screening technology, medicinal chemistry's transition from an art to a science is benefiting from a wealth of new software products, spanning both bio- and cheminformatics.  |
Bio-IT World April 16, 2004 Malorye Branca |
Finding the Perfect Fit Fragment-based drug discovery is unique and effective.  |
Bio-IT World January 21, 2005 |
Defining 'Integrative Genomics' Five experts from academia and industry discuss the burgeoning field of integrative genomics.  |
Chemistry World January 2012 |
Rising interest in compound bank David Fox argues for the creation of a centralized repository for small molecules to harness research efforts in drug discovery  |
Bio-IT World December 15, 2003 Malorye A. Branca |
Scenes from a Cell Breakthroughs are making cell-based screening faster, easier, more powerful.  |
Bio-IT World April 16, 2004 Kevin Davies |
The Matrix Revolutions Serenex, a company dedicated to drug discovery, uses a proprietary matrix, or affinity media, to bind purine-binding protiens - a process that could transform the drug discovery business.  |
Bio-IT World April 15, 2003 Mark D. Uehling |
Target Elimination Industry and FDA scientists turn to databases, applications software, and laboratory chips to move the safest, most effective molecules into clinical trials.  |
Bio-IT World July 11, 2002 Malorye Branca |
Deep Sequence Diving Like sailors of old, genomic data miners dream of discovering riches and fame. Given the recent improvements in analytics -- and a little more time -- they just might succeed.  |
Bio-IT World July 2005 Mark D. Uehling |
Hal, Open the Refrigerator Door Can a humble refrigerator make your high-throughput screening (HTS) campaigns more productive? Yes, Eli Lilly discovered. The TekCel robots can deliver plates (and data) more quickly than humans, at the rate of several hundred samples per hour, around the clock.  |
Bio-IT World November 2006 Alan S. Louie |
Signs of Life in Life Sciences IT Spending Pharmaceutical and other life science companies are confronting explosive growth in the volume of data being generated from R&D programs including high-throughput discovery instrumentation, molecular imaging (pre-clinical and clinical), and access to external data sources.  |
Bio-IT World July 2005 David M. Evans |
Cellular Imaging Takes Drug Discovery to New Heights The potential applications and ultimate value of high-content screening (HCS) and cellular image analysis are limited only by the imagination and expertise of the drug discovery groups using them to probe gene function and cell behavior.  |
Bio-IT World July 11, 2002 Kevin Davies |
Counting the Cost of Drug Discovery Much of the trouble ensnaring the drug industry is blamed on the exorbitant cost of drug discovery. Tangible proof that the bio-IT revolution will economize drug discovery is emerging, but there is still a long way to go.  |
Bio-IT World November 19, 2004 John Russell |
Sourcebook: Matters of Interpretation Michael O'Connell talks about trends in microarray and mass-spec data analysis and Insightful Corp.'s recent deal with visualization specialist Spotfire.  |
Bio-IT World June 2006 Robert M. Frederickson |
Tissue Microarray Hard and Software Technological advances in automated microscopes, digital image acquisition, and high-throughput screening techniques have led to the need for more sophisticated software tools, now offered through a collaboration between DMetrix, BioImagene, IBM and the Arizona Cancer Center.  |
Chemistry World October 2010 |
Column: In the pipeline Derek Lowe investigates the comeback combinatorial chemistry has made in the field of drug discovery  |
Chemistry World March 23, 2009 Hayley Birch |
Speeding up screening for chiral catalysts U.S. researchers say their method represents a 'standard workhorse' for discovery and optimisation of chiral catalysts, such as those widely used by the pharmaceutical and pesticide industries.  |
Bio-IT World Dec 2006/Jan 2007 Kevin Davies |
The NextBio Thing in Bioinformatics NextBio, which this fall officially introduced its platform after a year of beta testing by a handful of select organizations, aims to provide high-throughput information to researchers without them having to learn anything.  |
Fast Company November 2010 Elizabeth Svoboda |
The Myelin Repair Foundation Encourages Collaboration for a Cure Scientists in their labs. Big Pharma in pursuit of the next blockbuster. An innovative foundation brings them together to speed up the discovery of multiple-sclerosis drugs.  |
Bio-IT World March 2006 |
Bio-IT World Bio-IT 50 The 50 companies profiled here have driven and continue to drive the future of biomedical research and drug discovery: Accelrys... Affymetrix.. Apple... Becton Dickinson... BlueArc... 454 Life Sciences... etc.  |
Bio-IT World September 11, 2003 Malorye Branca |
The Odd Couple CombinatoRx brings matchmaking to drug discovery and development.  |
Bio-IT World January 21, 2005 Robert M. Frederickson |
High-Throughput Science Although genomic assays led the charge toward high-throughput science, new detection systems and formats are enabling the application of high-throughput techniques to proteins and cells.  |
Bio-IT World November 2006 Kevin Davies |
Building a Bridge Over Pharma with IT More than 100 enthusiastic delegates bridging the full breadth of the drug development pipeline gathered recently for the second annual Bridging Pharma and IT conference. Here are some highlights.  |
Bio-IT World August 18, 2004 Robert M. Frederickson |
Channeling HPLC Thoughts of high-throughput science has been a much broader trend toward high-throughput research and miniaturization, particularly in the pharmaceutical industry and in clinical medicine. Miniaturizing high-performance liquid chromatography (HPLC) makes it cheaper and faster.  |
Chemistry World April 2011 |
Molecular Obesity is Weighing Down Drug Discovery Medicinal chemistry's quest for potent drug candidates has resulted in molecules that are too large and too lipophilic for their own good.  |
Bio-IT World February 11, 2005 Mark D. Uehling |
New Software for HTS Discovery tools: a Columbia University laboratory information system named SLIMS (Small Laboratory Information System) picks old drug for new disease, spinal muscular atrophy.  |
Bio-IT World August 2005 |
Project Summaries Summaries of candidates for Bio-IT World's "Best Practices 2005" projects.  |
| Knowledge@Wharton |
A New Approach to Valuing Biotech Stocks Enormous swings in biotechnology stock prices during the last few weeks show how difficult it is for investors to value biotech companies. It's important to understand the invisible potential locked up in the organizational structure of biotechnology companies...  |
Reactive Reports Issue 52 David Bradley |
Interview with Gary Martin With more than 35 years experience in NMR spectroscopy, Gary Martin reveals some of the insights he has gained in this field.  |
Chemistry World December 2006 Derek Lowe |
Opinion: In the Pipeline A look at the story behind the growing investment by western companies in medicinal chemistry research in China.  |
Chemistry World August 23, 2012 Simon Campbell |
Protecting patients at all costs A new funding model is urgently required to deliver innovative medicines that meet the medical needs of the 21st century and contribute to economic growth.  |
The Motley Fool September 28, 2006 Ralph Casale |
A Second Sell-Off at Molecular Devices The company, which makes equipment used in drug development, is struggling with lumpy revenues.  |
Chemistry World September 2006 Yfke Hager |
Careers: Analytical Expertise After years of jumping between chemistry jobs, Adam Hold created his dream career by setting up his own company to provide analytical services.  |
Bio-IT World November 2005 |
Bridges and Boundaries in Drug Discovery Research Good communication, blurring cultural boundaries, and strong project governance may be as, if not more, important as sweeping technology solutions when it comes to converging discovery and IT and expediting drug development.  |
Bio-IT World August 13, 2002 Judith S. Hurwitz |
Software for Life Sciences: A Few Requests At the core of the life science revolution is IT. There is a discrepancy, however, between the emerging technology requirements and the preparedness of the technology industry to meet the needs of this market.  |
Bio-IT World September 2006 John A. Wass |
Integrating Knowledge The results of new mathematical routines have the potential to save pharmaceuticals millions of dollars in drug development. And yet the flow of successful drugs is dwindling. The problem goes beyond bureaucracy and lies in the complexity of the problem.  |
Bio-IT World Dec 2005/Jan 2006 Robert M. Frederickson |
Labcyte Demonstrates 'Sound' Transfer As mundane as the topic of fluid management may seem, it is big business. And this developer of microfluidic systems' new technology is well suited to high-throughput biological applications where large numbers of different fluids must be transferred rapidly and sequentially.  |